TEM Lactamase Engineering Databae version3.2
part of the BioCatNet
This Internet database integrates information on sequence, structure and function of TEM lactamases.
The BioCatNet Database System aims to collect and present comprehensive information about biocatalysts: sequence, structure, educts, products, environmental conditions and kinetics. Moreover, it will reveal structure-function relationships to boost development of novel biocatalysts.
To use the full set of tools or to contribute to the BioCatNet by posting functional information, please register.
A family-specific protein database in TEM lactamases. This repository was designed to support rational engineering of TEM lactamases.
Zeil C., Widmann M., Fademrecht S., Vogel C. & Pleiss J. (2016). Microdiversity of TEM β-lactamases: a network analysis of sequence-function relationships and exploration of sequence space. Antimicrob Agents Ch 60:2709-2717.
Widmann M. & Pleiss J. (2014). Protein variants form a system of networks: microdiversity of IMP metallo-beta-lactamases. PLoS ONE 9:e101813.
Widmann M., Pleiss J. & Oelschlaeger P. (2012). Systematic analysis of metallo-β-lactamases using an automated database. Antimicrob Agents Ch 56:3481-3491.
Thai K.Q. & Pleiss J. (2010). SHV Lactamase Engineering Database: a reconciliation tool for SHV β-lactamases in public databases. BMC Genomics 11: 563-563.
Thai Q.K., Bös F. & Pleiss J. (2009). The Lactamase Engineering Database: a critical survey of TEM sequences in public databases. BMC Genomics 10: 390